# Haemophagocytic lymphohistiocytosis and abdominal compartment syndrome in acute pancreatitis

**Authors:** Nishka Tapaswi, Hasib Ahmadzai, Alec J Hope, Oliver Fisher, Linda Y Zhang

PMC · DOI: 10.1093/jscr/rjaf813 · Journal of Surgical Case Reports · 2025-10-14

## TL;DR

This paper presents a rare case of HLH linked to severe pancreatitis and abdominal complications, emphasizing the need for early diagnosis and treatment.

## Contribution

The paper reports a rare association of HLH with necrotizing pancreatitis and abdominal compartment syndrome.

## Key findings

- HLH can occur as a complication of necrotizing pancreatitis.
- Abdominal compartment syndrome may develop as a severe consequence.
- Early diagnosis and treatment are critical for managing HLH in surgical patients.

## Abstract

Haemophagocytic lymphohistiocytosis (HLH) is a rare and often fatal syndrome that may be primary or secondary. This is a case of HLH associated with necrotizing pancreatitis, complicated by abdominal compartment syndrome. It highlights the need for high degree of suspicion for diagnosis in surgical patients, the complexity of managing the sequalae of HLH, and the importance of early treatment.

## Linked entities

- **Diseases:** acute pancreatitis (MONDO:0006515)

## Full-text entities

- **Diseases:** acute pancreatitis (MESH:D010195), abdominal compartment syndrome (MESH:D059325), HLH (MESH:D051359)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

5 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12526943/full.md

## References

14 references — full list in the complete paper: https://tomesphere.com/paper/PMC12526943/full.md

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Source: https://tomesphere.com/paper/PMC12526943