# Mimicking Alveolar Lung Structures with Lattice Designs

**Authors:** Aniello Riccio, Angela Russo, Andrea Sellitto, Maria Rosaria Barillari, Alfonso Reginelli, Salvatore Cappabianca

PMC · DOI: 10.3390/polym17192572 · 2025-09-23

## TL;DR

This study uses aerospace lattice design to create 3D-printed lung models for better surgical planning by mimicking alveolar structures.

## Contribution

Applying aerospace lattice design strategies to replicate human lung alveolar structures for biomedical use.

## Key findings

- Lattice structures were used to create anatomically accurate 3D-printed lung models.
- Finite element analyses showed the models' elasticity and density are suitable for simulating lung mechanics.
- A prototype with flexible resin provided realistic tactile feedback for surgical planning.

## Abstract

Advances in additive manufacturing (AM) have revolutionized various sectors, including aerospace engineering, where the use of lattice structures has enabled the development of lightweight high-performance components with optimized mechanical properties. Building on these engineering principles, this study explores the application of aerospace-derived lattice design strategies to the biomedical field, specifically for the replication of human lung alveolar structures. The objective is to create anatomically accurate 3D-printed lung models suitable for surgical planning. Finite element analyses have been conducted using a CAD model of adult lungs, including the application of lattice structures generated through nTopology software, to evaluate the elasticity and density, critical for simulating lung mechanics. A preliminary prototype has been produced using stereolithography and flexible resin, showing the potential for realistic tactile feedback.

## Full-text entities

- **Chemicals:** resin (MESH:D012116)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

19 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12526455/full.md

---
Source: https://tomesphere.com/paper/PMC12526455