Therapeutic Potential of Erythrina Genus: Bioactive Phytoconstituents with Potent Antiviral and Antimicrobial Activities
Muchtaridi Muchtaridi, Samuel Lestyawan, Maitsa Alya Fakhirah, Agus Rusdin, Shela Salsabila, Sandra Megantara, Anas Subarnas, Nur Kusaira Khairul Ikram
TL;DR
This review explores the Erythrina genus for its bioactive compounds that show strong antiviral and antimicrobial properties against various pathogens.
Contribution
The paper provides a comprehensive synthesis of Erythrina's therapeutic potential against drug-resistant pathogens.
Findings
Erythrina species show antiviral activity against HIV and SARS-CoV-2.
Strong antibacterial effects against multidrug-resistant Staphylococcus aureus were observed.
Antifungal and antiplasmodial effects were noted against Candida albicans and Plasmodium falciparum.
Abstract
Infectious diseases present a significant global health challenge, further exacerbated by the rising prevalence of antimicrobial resistance and the limited availability of effective antiviral and antimicrobial agents. The Erythrina genus has garnered scientific interest due to its diverse array of bioactive phytoconstituents, with potential therapeutic relevance. This review aims to synthesize and critically assess the existing literature on the antiviral, antibacterial, antifungal, and antiplasmodial properties of Erythrina species. A comprehensive literature search was conducted using PubMed, Scopus, and Google Scholar databases. Relevant studies were identified through keyword searches combining pathogen-specific terms with “Erythrina”. The extracted data were categorized based on the pathogen type and its associated bioactive compounds. Several Erythrina species exhibited…
Genes, proteins, chemicals, diseases, species, mutations and cell lines named across the full text — each resolved to its canonical identifier and authoritative record.
Click any figure to enlarge with its caption.
Figure 1
Figure 2
Figure 3
Figure 4
Figure 5
Figure 6
Figure 7
Figure 8
Figure 9Peer Reviews
No public reviews on file for this paper yet. If you reviewed it on a platform where reviews are public (OpenReview, ICLR, NeurIPS, ICML), you can paste yours below so the community can read it here.
Videos
No videos yet. Explain this paper in a talk, walkthrough, or lecture? Add one.
Taxonomy
TopicsBioactive natural compounds · Bioactive Compounds and Antitumor Agents · Phytochemistry and Biological Activities