# A Novel Electrochemical Sensor Based on Ti3C2Tx MXene/Mesoporous Hollow Carbon Sphere Hybrid to Detect Bisphenol A

**Authors:** Fei Cao, Qirong Zhou, Yanting Zhou, Yaqi Yang, Li Zhang, Yixi Xie

PMC · DOI: 10.3390/molecules30193992 · 2025-10-05

## TL;DR

This paper introduces a new electrochemical sensor using a Ti3C2Tx MXene and carbon sphere hybrid to detect the harmful chemical bisphenol A with high accuracy.

## Contribution

A novel Ti3C2Tx MXene/mesoporous hollow carbon sphere hybrid is developed for sensitive and accurate BPA detection.

## Key findings

- The sensor has a wide linear detection range of 10 to 200 μM for BPA.
- It achieves a low detection limit of 2.6 μM.
- The sensor successfully detects BPA in environmental water samples.

## Abstract

Bisphenol A (2,2-bis(4-hydroxyphenyl)propane, BPA), an endocrine-disrupting chemical with recognized adverse effects on human health and ecosystems, urgently requires convenient, sensitive, and accurate detection methods. In this study, a hierarchical heterostructure was fabricated by incorporating Ti3C2Tx MXene and mesoporous hollow carbon spheres (MHCs) to develop a high-performance electrochemical sensor for BPA. The nanocomposite was thoroughly characterized using SEM, TEM, and XRD, and then applied to modify a glassy carbon electrode (GCE). Under optimized conditions including pH and accumulation time, BPA detection was carried out via differential pulse voltammetry (DPV). The sensor exhibited a wide linear detection range from 10 to 200 μM and a low detection limit of 2.6 μM. Moreover, it was successfully applied to environmental water samples, demonstrating high accuracy and practicality for real-world BPA monitoring.

## Linked entities

- **Chemicals:** Bisphenol A (PubChem CID 6623), BPA (PubChem CID 6623)

## Full-text entities

- **Chemicals:** Ti3C2Tx MXene (-), 2,2-bis(4-hydroxyphenyl)propane (MESH:C006780), water (MESH:D014867), Carbon (MESH:D002244)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

5 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12526333/full.md

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Source: https://tomesphere.com/paper/PMC12526333