# The Greek Versions of the HLS19 Health Literacy Instruments (HLS19-NAV-GR, HLS19-COM-GR, and HLS19-VAC-GR): Translation, Cultural Adaptation, and Descriptive Pilot Evaluation

**Authors:** Angeliki Flokou, Panagiotis Theodorou, Dimitris A. Niakas, Petros Kostagiolas

PMC · DOI: 10.3390/healthcare13192541 · 2025-10-08

## TL;DR

This paper describes the translation and cultural adaptation of three health literacy instruments for use in Greece, along with initial evaluation of their performance.

## Contribution

The study provides a culturally adapted Greek version of the HLS19 health literacy instruments and reports on their initial psychometric properties.

## Key findings

- The Greek versions of the instruments were well accepted and required only minor revisions.
- Scales showed high short-term stability and good internal consistency.
- Item distributions skewed toward easy responses, with some items showing a ceiling effect.

## Abstract

Background: Health literacy (HL) is a key determinant of health outcomes and equity. The European Health Literacy Survey 2019 (HLS19) introduced three domain-specific instruments—HLS19-NAV, HLS19-COM-P-Q11, and HLS19-VAC. We present the translation, cultural adaptation, field testing, and descriptive pilot evaluation of their Greek versions (HLS19-NAV-GR, HLS19-COM-GR, HLS19-VAC-GR). Methods: Dual forward/back-translation and expert review (11 health professionals/academics) produced the final versions. A purposive, quota-guided field test (N = 71) approximated population distributions by sex, age, education, and geographical region. Test–retest stability (n = 16; ~12 days) was summarized primarily with intraclass correlation ICC (2,1), with Pearson/Spearman correlations reported secondarily. Internal consistency was assessed using ordinal alpha computed from polychoric (polytomous) and tetrachoric (dichotomous) correlations. We report item- and scale-level descriptive statistics for both the original polytomous (four-category, 1–4) responses and a dichotomous difficulty–ease scheme (1–2 vs. 3–4). Given the non-probability sampling in this pilot, the results are descriptive, not statistically representative. Results: Instruments were well accepted, requiring only minor revisions. Scales demonstrated high short-term stability and good internal consistency; inter-scale correlations were moderate, interpreted as associations among related but distinct constructs. Item distributions skewed toward Easy/Very Easy; several HLS19-VAC-GR items showed a clear ceiling, suggesting the need to consider harder items or a larger item pool in future validation. By scale, scores followed the descending order NAV, COM, and VAC. Distributions and ranking patterns broadly mirrored population-level findings from other countries. Conclusions: The adapted HLS19-NAV/COM/VAC-GR instruments are linguistically and culturally appropriate and prepared for large-scale validation, while items NAV9, COM4, and the VAC ceiling are flagged for further assessment.

## Full-text entities

- **Genes:** NUPR1 (nuclear protein 1, transcriptional regulator) [NCBI Gene 26471] {aka COM1, P8}, LIPC (lipase C, hepatic type) [NCBI Gene 3990] {aka HDLCQ12, HL, HTGL}, NAV2 (neuron navigator 2) [NCBI Gene 89797] {aka HELAD1, POMFIL2, RAINB1, STEERIN2, UNC53H2}, SCN2A (sodium voltage-gated channel alpha subunit 2) [NCBI Gene 6326] {aka BFIC3, BFIS3, BFNIS, DEE11, EA9, EIEE11}
- **Diseases:** HL (OMIM:603663), M (MESH:C566367), injury to (MESH:D014947)
- **Chemicals:** VAC (-)
- **Species:** Homo sapiens (human, species) [taxon 9606]
- **Cell lines:** HLS19 — Homo sapiens (Human), Transformed cell line (CVCL_K781)

## Figures

32 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12525262/full.md

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Source: https://tomesphere.com/paper/PMC12525262