# Patient Education and Communication in Palliative Radiotherapy: A Narrative Review

**Authors:** Erika Galietta, Costanza M. Donati, Filippo Mammini, Arina A. Zamfir, Alberto Bazzocchi, Rebecca Sassi, Renée Hovenier, Clemens Bos, Milly Buwenge, Silvia Cammelli, Helena M. Verkooijen, Alessio G. Morganti

PMC · DOI: 10.3390/cancers17193109 · Cancers · 2025-09-24

## TL;DR

Teaching patients about palliative radiotherapy improves their understanding and symptom control, but more research is needed to develop effective education strategies.

## Contribution

This review identifies that structured patient education at referral or during treatment improves knowledge, decision-making, and symptom outcomes in palliative radiotherapy.

## Key findings

- Education at the time of referral or consultation improves knowledge and reduces decisional uncertainty.
- Education during treatment improves symptom outcomes, including faster and more frequent pain control in bone metastases.
- Patients often have limited question-asking and hold curative expectations despite palliative intent.

## Abstract

Palliative radiotherapy (PRT) is used to relieve symptoms and preserve quality of life for people with advanced cancer, yet it is often offered late and is frequently misunderstood by patients and clinicians. We reviewed research on structured patient education and on how education and communication are delivered to adults referred to or receiving PRT. Six studies from 2005 to 2023 met our criteria, including two randomized trials. Education delivered at the time of referral or consultation improved knowledge, reduced decisional uncertainty, and increased readiness to proceed with PRT. Education delivered during treatment improved symptom outcomes, with one multicenter trial showing faster and more frequent pain control when pain education accompanied PRT for painful bone metastases. Observational and qualitative studies described limited patient question-asking and persistent curative expectations. Evidence remains scarce and heterogeneous, and pragmatic, scalable education that combines pre-consultation priming, clear goals-of-care language, and post-treatment reinforcement warrants testing.

Palliative radiotherapy (PRT) is central to symptom control in advanced cancer, yet referrals are often late, and patients and clinicians frequently hold misconceptions about intent, benefits, and logistics. Patient education may address these gaps, but the PRT-specific evidence base has not been consolidated. We conducted a narrative review following SANRA guidance. We searched PubMed, Scopus, and the Cochrane Library for English-language studies from 1 January 2000 to 18 July 2025. Eligible articles evaluated structured patient-education interventions or characterized education or communication content, information needs, or decision processes among adults referred to or receiving PRT. Two reviewers independently screened and extracted data. Owing to heterogeneity of designs and endpoints, we performed a narrative synthesis without meta-analysis. Six studies met criteria: two randomized controlled trials, two prospective pre–post studies, one qualitative interview study, and one observational communication study, conducted in the Netherlands, the United States, Canada, and Hong Kong. Education at referral or consultation improved knowledge, reduced decisional uncertainty, and increased readiness to proceed with PRT. Education integrated with treatment improved symptom outcomes, including higher rates of pain control at 12 weeks and faster time to pain control when a nurse-led pain-education program accompanied PRT for painful bone metastases, and improvements in dyspnea, fatigue, anxiety, and function in advanced lung cancer. Observational and qualitative work showed low patient question-asking and persistent curative expectations; overall quality of life generally did not change. Although the evidence is limited and heterogeneous, targeted, standardized education appears to improve decision quality and selected symptoms in PRT pathways. Pragmatic multi-site trials and implementation studies are needed to define content, timing, personnel, and delivery models that are scalable in routine care.

## Linked entities

- **Diseases:** cancer (MONDO:0004992)

## Full-text entities

- **Diseases:** pain (MESH:D010146), fatigue (MESH:D005221), cancer (MESH:D009369), bone metastases (MESH:D009362), anxiety (MESH:D001007), lung cancer (MESH:D008175), dyspnea (MESH:D004417)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## References

42 references — full list in the complete paper: https://tomesphere.com/paper/PMC12524152/full.md

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Source: https://tomesphere.com/paper/PMC12524152