# Rectal Mucosal Prolapse Syndrome: MRI and Endoscopic Images Mimicking Crohn’s Disease

## TL;DR

A rare condition called rectal mucosal prolapse can look like Crohn's disease in tests, leading to misdiagnosis and unnecessary treatment.

## Contribution

This case highlights the importance of distinguishing rectal mucosal prolapse from Crohn's disease to avoid inappropriate corticosteroid use.

## Key findings

- RMPS can mimic CD with symptoms like ulceration and stricture.
- Endoscopic resection is key to confirming RMPS diagnosis.
- Chronic prolapse can cause secondary inflammation resembling CD.

## Abstract

Rectal mucosal prolapse syndrome (RMPS) is a rare condition that mimics Crohn’s disease (CD) in imaging and endoscopy. We present a 29-year-old male with rectal tenesmus and a mid-rectal mass initially diagnosed as CD based on colonoscopy and MRI. After failed corticosteroid therapy, endoscopic resection revealed fibromuscular obliteration pathognomonic for RMPS. Chronic prolapse may induce secondary inflammation mimicking CD (including ulceration, stricture, and pseudofistulation), necessitating careful differential diagnosis to avoid unwarranted corticosteroid therapy.