# Complete thoracoscopic resection for TXN2aM0 primary lung cancer: a case series with 5-year follow-up

**Authors:** Daiki Yoshikawa, Takeshi Kawaguchi, Ryo Miyata, Keiji Yamanashi, Maiko Takeda, Akihiko Yoshizawa, Takao Osa, Kazuya Tanimura, Shigeto Hontsu, Shigeo Muro, Sachiko Miura, Mitsuharu Hosono, Masatsugu Hamaji

PMC · DOI: 10.1186/s44215-025-00228-z · 2025-10-14

## TL;DR

This case series shows that complete thoracoscopic resection of TXN2aM0 lung cancer can lead to long-term survival, but recurrence is possible.

## Contribution

Presents long-term follow-up data on thoracoscopic resection for TXN2aM0 lung cancer, highlighting recurrence risks.

## Key findings

- Four patients survived 5 to 10 years after complete thoracoscopic resection of TXN2aM0 lung cancer.
- Two patients experienced local recurrence at 2 and 5 years postoperatively.
- Complete resection may offer long-term survival, but late recurrence remains a concern.

## Abstract

Management of resectable TXN2aM0 primary lung cancer is controversial, and data regarding the long-term outcomes and guideline recommendations for such cases are lacking. We present the characteristics and long-term outcomes of four patients who underwent complete thoracoscopic resection of TXN2aM0 primary lung cancer. All patients experienced an uneventful postoperative course and survived for 5 to 10 years postoperatively; however, one patient experienced local recurrence at 2 years postoperatively and one patient experienced local recurrence at 5 years postoperatively. Our limited experience suggested that long-term survival may be achieved with complete resection of TXN2aM0; however, late recurrence and local recurrence are possible.

## Linked entities

- **Diseases:** lung cancer (MONDO:0005138)

## Full-text entities

- **Diseases:** lung cancer (MESH:D008175)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12522338/full.md

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Source: https://tomesphere.com/paper/PMC12522338