# Detection of Colpodella sp. in blood of an ICU patient in Guizhou Province, China: a preliminary molecular report

**Authors:** Xiaopeng Yang, Yisong Dai, Jiashun Yu, Jixia Tang, Xingxing Chen, Qiu Chen, Wuchun Cao, Jiahong Wu, Fuxun Yu, Lin Zhan

PMC · DOI: 10.3389/fmed.2025.1638864 · 2025-10-01

## TL;DR

This paper reports the first case of Colpodella sp. infection in a human in Guizhou Province, China, suggesting it could be an emerging health threat.

## Contribution

The study documents the first confirmed human case of Colpodella sp. in Guizhou Province, China.

## Key findings

- Colpodella sp. was detected in the blood of an ICU patient in Guizhou Province.
- This is the first reported human infection with Colpodella sp. in the region.

## Abstract

Colpodella sp. is an emerging tick-borne protozoan that causes fever, anemia, and neurological symptoms. Although this protozoan has previously been identified in animals and ectoparasite vectors within Guizhou Province, its prevalence among human populations remains unclear. We report a case of Colpodella sp. infection in a patient admitted to the intensive care unit (ICU) of a tertiary hospital in Guizhou Province, China. This case represents the first documented human infection with Colpodella sp. in this region, highlighting its potential as an emerging pathogen. Our findings provide preliminary evidence of human infection and underscore the urgent need for further epidemiological studies to evaluate the public health implications of Colpodella sp.

## Linked entities

- **Diseases:** anemia (MONDO:0002280)
- **Species:** Colpodella sp. (taxon 2033693)

## Full-text entities

- **Diseases:** anemia (MESH:D000740), fever (MESH:D005334), neurological symptoms (MESH:D009461), infection (MESH:D007239)
- **Species:** Colpodella sp. (species) [taxon 2033693], Homo sapiens (human, species) [taxon 9606]

## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC12521428/full.md

---
Source: https://tomesphere.com/paper/PMC12521428