# Branch Retinal Artery Occlusion in a Young Adult: A Diagnostic Clue to Systemic Embolic Risk

**Authors:** Justin Nguyen, Jasmine Q Nguyen, Julia C Moore, Briana Krutsinger, Matthew D Overturf

PMC · DOI: 10.7759/cureus.92291 · Cureus · 2025-09-14

## TL;DR

A young woman with a history of heart valve replacement developed a rare eye condition linked to a possible blood clot, highlighting the need for systemic evaluation.

## Contribution

This case highlights BRAO in a young adult as a diagnostic clue for systemic embolic risk from cardiac sources.

## Key findings

- A 41-year-old woman with a mechanical aortic valve developed chronic BRAO due to a suspected calcific embolus.
- The patient showed visual field loss and inner retinal atrophy consistent with the BRAO diagnosis.
- Coordinated care with cardiology and anticoagulation adjustment led to stable vision at six months.

## Abstract

Branch retinal artery occlusion (BRAO) is characterized by the blockage of one or more of the smaller branches of the central retinal artery, resulting in localized retinal ischemia and potential abrupt vision impairment. Typically occurring in older adults, BRAO is frequently linked to embolic events originating from carotid or cardiac sources, such as cholesterol or calcific plaques. Conversely, BRAO in younger individuals is uncommon and often indicates an atypical systemic etiology. Cardiac conditions, including valvular disease and replacement heart valves, have been documented as embolic sources in such instances. This case report details a 41-year-old woman with a prior history of a mechanical aortic valve replacement who developed chronic BRAO potentially attributed to a suspected calcific embolus. Her evaluation revealed a calcific embolus causing inferior temporal BRAO with corresponding visual field loss and inner retinal atrophy. She was co-managed with a systemic stroke workup, cardiology, resulting in warfarin dose adjustment, and reported stable vision at six-month follow-up.

## Linked entities

- **Diseases:** Branch retinal artery occlusion (MONDO:0001630), stroke (MONDO:0005098)

## Full-text entities

- **Diseases:** vision impairment (MESH:D014786), Embolic (MESH:D004617), retinal atrophy (MESH:D012173), BRAO (MESH:D015356), stroke (MESH:D020521), valvular disease (MESH:D006349)
- **Chemicals:** cholesterol (MESH:D002784), warfarin (MESH:D014859)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC12520454/full.md

## Figures

6 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12520454/full.md

## References

23 references — full list in the complete paper: https://tomesphere.com/paper/PMC12520454/full.md

---
Source: https://tomesphere.com/paper/PMC12520454