# Exploring the relationship between clinical symptoms and MRI findings in temporomandibular joint disorders: a preliminary study

**Authors:** Ecem Sancar, Dilek Yılmaz, Safak Parlak, Elif G. Bulut, Gozde Ozer, Nur E. Hersek

PMC · DOI: 10.22514/jofph.2025.059 · Journal of Oral & Facial Pain and Headache · 2025-09-12

## TL;DR

This study explores how MRI findings in jaw joint disorders relate to symptoms like pain and joint sounds in patients.

## Contribution

The study identifies specific MRI findings linked to clinical symptoms in temporomandibular joint disorders.

## Key findings

- Disc displacement is significantly associated with joint pain and sounds.
- Condylar degeneration is common but has limited clinical impact except for reducing joint sounds.
- Disc deformity is strongly correlated with condylar degeneration and joint effusion.

## Abstract

Background: This study aimed to evaluate the relationships between 
magnetic resonance imaging (MRI) findings (such as condylar degeneration, disc 
displacement, joint effusion and disc deformity) and clinical symptoms in 
patients with temporomandibular joint disorders (TMDs). Methods: A total of 54 patients (108 temporomandibular joints (TMJs)) were included. 
Clinical evaluations assessed joint pain, joint sounds, mouth opening 
limitations, deviation/deflection and locking. MRI scans were analyzed for 
condylar degeneration, disc displacement (disc displacement with reduction (DDWR) 
or disc displacement without reduction (DDWOR)), joint effusion, and disc 
morphology. Statistical analyses included chi-square tests/Fisher’s exact tests 
for categorical variables. A p value < 0.05 was considered to be 
statistically significant. Results: DDWR and DDWOR were 
significantly associated with joint pain (p = 0.044) and sounds 
(p = 0.032). Joint effusion demonstrated no clear correlation with 
clinical symptoms. Condylar degeneration was frequently observed but had limited 
clinical impact, except for a reduction in joint sounds (p = 0.03). 
Moreover, disc deformity was significantly correlated with condylar degeneration 
and joint effusion (p < 0.001). Conclusions: MRI findings 
provide valuable insights into the structural changes observed in TMDs. Although 
disc displacement is strongly linked to pain and joint sounds, condylar 
degeneration and effusion exhibit more complex relationships with clinical 
symptoms.

## Full-text entities

- **Diseases:** joint pain (MESH:D018771), Joint effusion (MESH:D000080324), disc displacement (MESH:D007405), pain (MESH:D010146), Condylar degeneration (MESH:C538270), disc deformity (MESH:D055959), TMDs (MESH:D013705)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12520446/full.md

## References

24 references — full list in the complete paper: https://tomesphere.com/paper/PMC12520446/full.md

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Source: https://tomesphere.com/paper/PMC12520446