# The Effects and Adverse Reactions of Different Bowel Cleansers on Gut Microbiota After Colonoscopy

**Authors:** Jiabin Hu, Xiongqun Peng, Shuang Cai, Jiaojiao Qiu, Shuxia Wang, Ping Zhu

PMC · DOI: 10.5152/tjg.2025.25150 · The Turkish Journal of Gastroenterology · 2025-08-11

## TL;DR

This paper examines how different bowel cleansers used before colonoscopies affect gut microbiota and may impact health.

## Contribution

The study provides a detailed analysis of how various laxatives influence gut microbiota and their potential adverse effects.

## Key findings

- Bowel preparation quality affects colonoscopy effectiveness and gut microbiota balance.
- Different laxatives may disrupt gut microbiota in distinct ways.
- There is a need for more comprehensive clinical references for laxative selection.

## Abstract

Colonoscopy is a pivotal technique for screening and diagnosing colorectal diseases, particularly colorectal polyps and cancers. Early detection of lesions enables early diagnosis and treatment, thereby improving patient prognosis. The adequacy of bowel preparation is directly related to the quality and effectiveness of colonoscopy. However, the bowel cleansing process may disrupt the balance of gut microbiota, subsequently affecting the host’s health status. Currently, there is a relative scarcity of reports on the specific impacts of different types of laxatives on gut microbiota. Therefore, this paper aims to deeply analyze and summarize the effects of various bowel preparations on gut microbiota and their potential adverse reactions following colonoscopy, providing a more comprehensive reference for the selection of bowel preparations in clinical practice.

## Full-text entities

- **Diseases:** cancers (MESH:D009369), colorectal diseases (MESH:D015179), colorectal polyps (MESH:D003111)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC12520138/full.md

## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC12520138/full.md

## References

46 references — full list in the complete paper: https://tomesphere.com/paper/PMC12520138/full.md

---
Source: https://tomesphere.com/paper/PMC12520138