# Bibliometric analysis of global research trends and development prospects of Smilax glabra Roxb using CiteSpace

**Authors:** Wenqing Shi, Xiao Li, Xin Zhao, Jingjing Jiang, Chenxi Wang, Guorong Fan, Yuefen Lou

PMC · DOI: 10.3389/fpls.2025.1651650 · Frontiers in Plant Science · 2025-09-30

## TL;DR

This paper analyzes global research trends on Smilax glabra Roxb, a medicinal plant used for treating gout and other conditions, using bibliometric tools to identify key contributors, topics, and future directions.

## Contribution

The study provides the first comprehensive bibliometric analysis of Smilax glabra Roxb research, revealing emerging trends and key research areas.

## Key findings

- English publications on Smilax glabra Roxb are increasing steadily.
- Key research areas include anti-inflammatory effects and network pharmacology.
- Future research is expected to integrate bioinformatics with animal studies.

## Abstract

Smilax glabra Roxb (SGR) is extensively utilized in the management of disorders, including hyperuricemia and gout, due to its notable pharmacological effects, and it is also the primary component in the functional food turtle jelly. Despite extensive research on SGR, no systematic statistical analysis of the literature has been conducted on it. This study provides a comprehensive bibliometric analysis of SGR, identifies the current research landscape, identifies hotspots, and performs trend analysis.

All Chinese and English literatures pertaining to SGR was gathered from Web of Science Core Collection (WoSCC), China Knowledge Network (CNKI), Wanfang database, and VIP database, subsequently de-duplicated and organized, with CiteSpace software employed for visualization and analysis of the literature.

A total of 1723 articles were incorporated into the analysis, and the quantity of SGR-related publications in English persists in its upward trajectory. Sun Weifeng, Lisa Dong, and Zhang Qingfeng emerged as the principal contributors, while Beijing University of TCM and Zhejiang University of TCM established themselves as the foremost publishing organizations. Noteworthy, keywords indicative of contemporary research focal points encompassed “Chinese medicine treatment,” “gout,” “anti-inflammatory,” and “network pharmacology.”

The investigation into SGR concentrates on pharmaceuticals and their active components, therapeutic interventions, and pharmacological mechanisms. Recently, anti-inflammatory and cyberpharmacology have emerged as prominent trends, indicating that the integration of animal studies with molecular bioinformatics to investigate the pharmacological mechanism of SGR is the main research direction in the future, while cardiovascular protection and neuroprotective effects have become significant areas of recent inquiry. Consequently, SGR is anticipated to be a functional plant for the treatment of various diseases.

## Linked entities

- **Diseases:** gout (MONDO:0005393), hyperuricemia (MONDO:0002144)

## Full-text entities

- **Diseases:** gout (MESH:D006073), inflammatory (MESH:D007249), hyperuricemia (MESH:D033461)
- **Chemicals:** SGR (-)

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC12519948/full.md

## Figures

9 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12519948/full.md

## References

43 references — full list in the complete paper: https://tomesphere.com/paper/PMC12519948/full.md

---
Source: https://tomesphere.com/paper/PMC12519948