First person – Jack Barrington

TL;DR

This paper explores how interleukin-1 affects myeloid cells and blood flow in the brain after a hemorrhage.

Contribution

The study reveals a novel role for interleukin-1 in regulating immune cell movement and cerebral blood flow post-intracerebral hemorrhage.

Findings

Interleukin-1 influences myeloid cell trafficking after brain hemorrhage.

It also modulates cerebral blood flow following the injury.

These findings highlight interleukin-1's role in post-hemorrhage brain recovery.

Abstract

First Person is a series of interviews with the first authors of a selection of papers published in Disease Models & Mechanisms, helping researchers promote themselves alongside their papers. Jack Barrington is first author on ‘
Interleukin-1 regulates myeloid cell trafficking and cerebral blood flow following intracerebral haemorrhage’, published in DMM. Jack conducted the research described in this article while a PhD student in Stuart M. Allan's lab at The University of Manchester, Manchester, UK. He is now a postdoctoral research fellow in the lab of Barry McColl at The University of Edinburgh, Edinburgh, UK, investigating immune contributions to brain health and disease.

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