# Arterial Spin Labeled MRI to Detect Early Placental Perfusion Differences in Fetal Heart Disease

**Authors:** Rachel L. Leon, Marjorie Navalta, Joshua S. Greer, Ananth J. Madhuranthakam, Durga Udayakumar

PMC · DOI: 10.1001/jamanetworkopen.2025.37282 · 2025-10-13

## TL;DR

This study explores using ASL MRI to detect early placental perfusion changes in pregnancies affected by fetal heart disease.

## Contribution

The novelty lies in applying ASL MRI to assess placental perfusion in fetal heart disease.

## Key findings

- ASL MRI can quantify placental perfusion in pregnancies with fetal heart disease.
- Early placental perfusion differences may be detectable in these pregnancies.

## Abstract

This cohort study evaluates the use of arterial spin labeling magnetic resonance imaging (ASL MRI) to quantify placental perfusion in pregnant individuals with a fetus with congenital heart disease.

## Linked entities

- **Diseases:** congenital heart disease (MONDO:0005453)

## Full-text entities

- **Diseases:** Fetal Heart Disease (MESH:D005315)
- **Chemicals:** Spin (-)

## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12519309/full.md

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Source: https://tomesphere.com/paper/PMC12519309