# A Rare Case Report of Morvan Syndrome: A Constellation of Autonomic, Central and Peripheral Nervous System Involvement

## TL;DR

This paper reports a rare case of Morvan syndrome, a severe autoimmune neurological disorder involving multiple nervous system components.

## Contribution

The novelty lies in presenting a rare case from South India, contributing to the limited global case literature on Morvan syndrome.

## Key findings

- Morvan syndrome involves autonomic, central, and peripheral nervous system symptoms.
- Antibodies against voltage-gated potassium channels are associated with the disease.
- Treatment with immunosuppression and plasmapheresis is effective.

## Abstract

Morvan syndrome is an extremely rare neurological autoimmune entity that can be life-threatening for the patient if not detected early. It consists of features of autonomic, peripheral, and central nervous systems, which include fluctuating blood pressure, insomnia, delirium, cognitive decline, hyperhidrosis, and peripheral nerve hyperexcitability in the form of myokymia. It is named after the famous French physician Augustin Marie Morvan. Antibodies against voltage-gated potassium channels have been implicated in this disease. Appropriate immunosuppression and plasmapheresis are commonly used to treat this disease. We present a rare case report of Morvan syndrome from a tertiary care center in Karnataka, South India.