# Tenosynovial Giant Cell Tumors: A Musculoskeletal Case Series

**Authors:** Franco C Yip, Yung Kong Wong, Wing Ho Chong, On Chee Li, Kai Yan Kwok

PMC · DOI: 10.7759/cureus.92200 · Cureus · 2025-09-13

## TL;DR

This case series explores the varied presentations and diagnostic challenges of tenosynovial giant cell tumors to improve clinical recognition and management.

## Contribution

The study contributes a detailed case series highlighting diagnostic challenges and imaging features of TSGCT.

## Key findings

- TSGCTs often present with nonspecific symptoms, leading to misdiagnosis.
- Characteristic imaging findings can aid in accurate diagnosis of TSGCT.
- Early recognition is crucial to prevent debilitating outcomes in TSGCT patients.

## Abstract

Tenosynovial giant cell tumors (TSGCT) are uncommon soft tissue neoplasms that can become debilitating if not diagnosed and treated promptly, particularly in advanced stages. Because of their nonspecific clinical manifestations, they are often misdiagnosed or overlooked. This case series highlights the varied clinical presentations and characteristic imaging findings of patients with TSGCT. By addressing key diagnostic challenges and pitfalls, the study aims to improve awareness and enhance diagnostic accuracy, thereby supporting timely and effective management in clinical practice.

## Linked entities

- **Diseases:** Tenosynovial giant cell tumors (MONDO:0024686), TSGCT (MONDO:0024686)

## Full-text entities

- **Diseases:** TSGCT (MESH:D000070779), soft tissue neoplasms (MESH:D012983)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

7 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12516795/full.md

## References

7 references — full list in the complete paper: https://tomesphere.com/paper/PMC12516795/full.md

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Source: https://tomesphere.com/paper/PMC12516795