# Clinical Outcomes of Large-Bore Aspiration Thrombectomy for Tumor Pulmonary Embolism in Renal Cell Carcinoma

**Authors:** Anand Mulji, Tony Rizk, Yara Younan, Stephen Stringfellow, Antony Gayed

PMC · DOI: 10.1016/j.jaccas.2025.105358 · JACC Case Reports · 2025-10-08

## TL;DR

A 66-year-old man with kidney cancer had a successful treatment for a tumor blockage in his lung, with no recurrence after four years.

## Contribution

Demonstrates long-term efficacy of large-bore aspiration thrombectomy in managing tumor pulmonary embolism.

## Key findings

- No disease recurrence was observed over four years following the procedure.
- The procedure provided both therapeutic and diagnostic benefits.
- Large-bore aspiration thrombectomy enabled histopathologic analysis for treatment guidance.

## Abstract

We present a 4-year longitudinal follow-up of a previously reported case involving a 66-year-old man with renal cell carcinoma who underwent radical nephrectomy, complicated by a massive pulmonary artery tumor embolism treated with large-bore aspiration thrombectomy. Serial clinical evaluations and imaging over 4 years have shown no evidence of disease recurrence following the initial intervention. This case underscores the evolving role of emergent large-bore aspiration thrombectomy in oncologic settings, not only as a therapeutic intervention but also for its diagnostic utility in enabling histopathologic characterization and guiding oncologic management.

Large-bore aspiration thrombectomy may offer long-term disease control in cases of tumor pulmonary embolism. This procedure can aid diagnosis and inform oncologic treatment planning through tissue acquisition.

## Linked entities

- **Diseases:** renal cell carcinoma (MONDO:0005086)

## Full-text entities

- **Diseases:** Renal Cell Carcinoma (MESH:D002292), Tumor Pulmonary Embolism (MESH:D009360)

## Full text

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## Figures

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## References

3 references — full list in the complete paper: https://tomesphere.com/paper/PMC12516271/full.md

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Source: https://tomesphere.com/paper/PMC12516271