# Aseptic Meningitis as First Presentation of Acute Myeloid Leukemia With Normal Cell Blood Count

## TL;DR

Aseptic meningitis can be the first sign of acute myeloid leukemia, even with normal blood counts, requiring careful evaluation to avoid delayed diagnosis.

## Contribution

Highlights that AML can present with aseptic meningitis and normal CBC, emphasizing the need for thorough differential diagnosis.

## Key findings

- Aseptic meningitis may be the initial manifestation of AML despite normal blood counts.
- A single CSF analysis for malignant cells may be insufficient and delay diagnosis.
- Leukemias should be considered in the differential diagnosis of aseptic meningitis.

## Abstract

Aseptic meningitis can be the initial manifestation of acute myeloid leukemia (AML), even when the complete blood count (CBC) is normal. A single cerebrospinal fluid (CSF) analysis for malignant cells may be insufficient and could delay diagnosis. Therefore, infections, collagen vascular diseases, and malignancies—particularly leukemias—should be carefully considered.