# Angina Bullosa Hemorrhagica of the Oral Mucosa: A Case Report

**Authors:** Prarthana Sudeep, Krishna Santhosh Kumar, Aravind MS, Renju Jose

PMC · DOI: 10.7759/cureus.92123 · 2025-09-12

## TL;DR

This case report describes a rare, harmless condition called angina bullosa hemorrhagica that causes blood blisters in the mouth, which heal on their own.

## Contribution

The paper contributes a case report to increase awareness and understanding of angina bullosa hemorrhagica for accurate diagnosis.

## Key findings

- ABH presents as sudden blood-filled blisters in the oral cavity, often on the palate or oropharynx.
- The blisters typically rupture within a day or two and heal without scarring or further pain.
- ABH is not linked to systemic diseases but may occur in patients with diabetes or hypertension.

## Abstract

Angina bullosa hemorrhagica (ABH) is a rare and benign condition characterized by the abrupt emergence of one or more blisters filled with blood inside the oral cavity. These blood-filled vesicles and bullae, which appear on the palate or oropharynx, are acute and occasionally painful. Its etiopathogenesis is unclear; however, it cannot be linked to systemic illnesses, vesiculobullous disorders, blood dyscrasias, or any other recognized cause. They were also identified in patients who use topical steroids or have diabetes mellitus or hypertension. Usually, the blisters burst within a day or two and heal on their own without causing any more pain or scars. The lesions are typically isolated and may cause patient anxiety due to a sudden onset. This case report’s primary goal is to raise awareness to prevent misdiagnosis and improper treatment of the condition.

## Linked entities

- **Diseases:** diabetes mellitus (MONDO:0005015)

## Full-text entities

- **Diseases:** vesiculobullous disorders (MESH:D012872), hypertension (MESH:D006973), pain (MESH:D010146), blood dyscrasias (MESH:D006402), diabetes mellitus (MESH:D003920), systemic illnesses (MESH:D012140), anxiety (MESH:D001007), ABH (MESH:D011695)
- **Chemicals:** steroids (MESH:D013256)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12515376/full.md

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Source: https://tomesphere.com/paper/PMC12515376