# Trauma Revealing a Tumour: A Case Report

**Authors:** Allan Zhou, Claire Liegeois, Suraya Zainal Abidin, Eunizar Omar

PMC · DOI: 10.7759/cureus.88151 · Cureus · 2025-07-17

## TL;DR

A 25-year-old man's knee injury led to the discovery of an undiagnosed bone tumor, emphasizing the importance of thorough evaluation in similar cases.

## Contribution

This case report highlights how trauma can reveal hidden bone tumors, contributing to clinical awareness and diagnostic practices.

## Key findings

- A lytic lesion in the left lateral femoral condyle was identified through imaging.
- Immunohistochemical staining confirmed the diagnosis of giant-cell tumour of bone.
- The patient underwent successful curettage, bone grafting, and internal fixation.

## Abstract

A 25-year-old male patient presented to the emergency department with acute left knee pain and swelling after a fall. He had been experiencing left knee pain for several months. Examination revealed a swollen left knee held in a flexed position with limitation in range of motion. Plain radiographs performed showed a lytic lesion over the left lateral femoral condyle, and the patient was admitted for computed tomography (CT) and magnetic resonance imaging (MRI) scans. An open biopsy was performed, and immunohistochemical staining of the tumour cells was positive for H3G34W, confirming the diagnosis of giant-cell tumour of bone (GCTB). The patient subsequently underwent left distal femur GCTB curettage, bone grafting, and internal fixation. This case highlights how incidental trauma can reveal a previously undiagnosed bone tumour, underscoring the need for clinicians to maintain a high index of suspicion when evaluating patients.

## Full-text entities

- **Diseases:** lytic lesion (MESH:D009059), Trauma (MESH:D014947), Tumour (MESH:D009369), swelling (MESH:D004487), bone tumour (MESH:D001859), GCTB (MESH:D018212), knee pain (MESH:D046788)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12358094/full.md

## References

7 references — full list in the complete paper: https://tomesphere.com/paper/PMC12358094/full.md

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Source: https://tomesphere.com/paper/PMC12358094