# Efficacy of colchicine in oral submucous fibrosis: A systematic review and meta-analysis

## TL;DR

This paper reviews the effectiveness of colchicine in treating oral submucous fibrosis, focusing on symptom improvement in Asian populations.

## Contribution

The study provides a systematic review and meta-analysis to clarify colchicine's role in treating oral submucous fibrosis.

## Key findings

- Colchicine may help alleviate symptoms like burning sensation in OSMF patients.
- The drug shows potential in improving mouth opening in affected individuals.

## Abstract

One of the potentially malignant disorders of the oral mucosa in Asian nations is known as oral submucous fibrosis (OSMF). The drug,
surgical and combination therapies are some of the several OSMF treatment options. The importance of colchicine in the treatment of oral
submucous fibrosis is still unclear. Therefore, it is of interest to review the efficacy of colchicine in oral submucous fibrosis in
terms of improving symptoms such as burning sensation and mouth opening. Known data shows colchicine is in alleviating these symptoms in
OSMF patients.