# Alpha gal syndrome - A rare case report in South India

**Authors:** Suganya Sribalaji, Asmathulla S., Manavalan J.

PMC · DOI: 10.6026/973206300210982 · Bioinformation · 2025-05-31

## TL;DR

A 31-year-old woman in South India experienced allergic reactions after eating red meat, likely due to a tick bite, indicating a rare case of Alpha gal syndrome.

## Contribution

This is the first reported case of Alpha gal syndrome in South India.

## Key findings

- The patient had anaphylactic reactions linked to red meat consumption following a tick bite.
- Elevated serum IgE levels supported the diagnosis of Alpha gal syndrome.
- No prior cases of this syndrome have been documented in South India.

## Abstract

A 31-year-old female presented with complaints of itching with previous history of 5-6 anaphylactic reactions since last one month.
Her symptoms were preceded (3-6 hours) with intake of red meat. She suffered one tick bite (probably a lone star tick) one month before
the allergic episodes. Laboratory tests showed elevated serum IgE levels. She was suspected to suffer from Alpha gal syndrome. It is a
disease causally linked to bites from ticks. Although cases of alpha-gal allergy have already been reported in a few European countries,
to our best knowledge, no cases have been reported so far in South India. She was managed with steroids and dietary restrictions.

## Linked entities

- **Diseases:** Alpha gal syndrome (MONDO:0100001)

## Full-text entities

- **Diseases:** Alpha gal syndrome (MESH:C000655084), itching (MESH:D011537), allergic (MESH:D004342), tick bite (MESH:D064927)
- **Chemicals:** alpha-gal (MESH:C055075), steroids (MESH:D013256)

## Full text

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## References

11 references — full list in the complete paper: https://tomesphere.com/paper/PMC12357717/full.md

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Source: https://tomesphere.com/paper/PMC12357717