# Impact of peak expiratory flow rate in general and regional anesthesia: A comparative study

**Authors:** Dinesh M., Suganya S., Yugesh Kesavamoorthy, Sowmiya T., Marimuthu M., Sangeetha S.

PMC · DOI: 10.6026/973206300211082 · Bioinformation · 2025-05-31

## TL;DR

This study compares how general and regional anesthesia affect peak expiratory flow rate, finding a significant drop after general anesthesia.

## Contribution

The study provides new evidence on the differential impact of anesthesia types on respiratory function.

## Key findings

- General anesthesia significantly reduces peak expiratory flow rate post-operatively.
- Respiratory rate also decreases significantly after surgery under general anesthesia.
- Regional anesthesia does not cause a notable change in peak expiratory flow rate.

## Abstract

Anesthesia can have a significant impact on Peak expiratory flow rate (PEFR) due to several factors that leads to partial airway
blockage and restriction air flow making it harder to exhale forcefully. A sample size of 150 study participants was taken, among which
75 subjects were undergone general anesthesia and 75 subjects undergone regional anesthesia. We categorize the participants into 2
groups, where group 1 receives general anesthesia and group 2 receives regional anesthesia. The subjects were selected based on
inclusion and exclusion criteria. PEFR (336.02 ± 52.35) and Respiratory rate (16.07 ± 2.42) were found to be drastically
reduced in post-operative when compared to pre-operative which was statistically significant (P<0.05). Therefore, it is observed that
PEFR is significantly reduced in patients receiving general anesthesia during post-operative period where there is no much change in
regional anesthesia.

## Full-text entities

- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## References

19 references — full list in the complete paper: https://tomesphere.com/paper/PMC12357716/full.md

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Source: https://tomesphere.com/paper/PMC12357716