# Correlation between endo-perio lesions and systemic diseases: A cross-sectional study

**Authors:** Rahul Singh, Nidhi Singh, Simran Chauhan, Lubna Tabassum Siddiqui, Lucy Bhola, Madhuri S. Sale, Vinayak Meharwade, Prabu Mahin Syed Ismail, Abhigyan Manas

PMC · DOI: 10.6026/973206300211144 · Bioinformation · 2025-05-31

## TL;DR

This study finds a strong link between endo-perio lesions and systemic diseases, particularly in older males.

## Contribution

The study provides new insights into the association between endo-perio lesions and systemic diseases in a large sample.

## Key findings

- Systemic diseases are strongly correlated with the severity of endo-perio lesions.
- Older males show a higher prevalence of severe endo-perio lesions.
- Lesions were classified into primary endodontic, primary periodontal, or combined types.

## Abstract

The correlation between endo-perio lesions and systemic diseases and to analyze their association with age and gender distribution is
of interest. Hence, a total of 800 participants aged between 25 and 75 years. Patients were categorized based on the presence or absence
of systemic diseases, including diabetes, hypertension, cardiovascular disorders, arthritis and altered kidney/liver function. Detailed
clinical and radiographic evaluations were conducted to classify lesions as primary endodontic, primary periodontal, or true combined
lesions. The study underscores a strong correlation between systemic diseases and the severity of endo-perio lesions, especially in
older males.

## Linked entities

- **Diseases:** diabetes (MONDO:0005015), arthritis (MONDO:0005578)

## Full-text entities

- **Diseases:** systemic diseases (MESH:D034721), hypertension (MESH:D006973), diabetes (MESH:D003920), arthritis (MESH:D001168), cardiovascular disorders (MESH:D002318)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## References

19 references — full list in the complete paper: https://tomesphere.com/paper/PMC12357700/full.md

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Source: https://tomesphere.com/paper/PMC12357700