# Clinico-pathological analysis of oral red and white mucosal lesions in iron-deficiency anemia among non-tobacco-users

**Authors:** Randhir Kumar, Geeta Sharma, Meenu Taneja Bhasin, Sharib Abdus Salam, Atul Anand Bajoria

PMC · DOI: 10.6026/973206300210973 · Bioinformation · 2025-05-31

## TL;DR

This study explores the link between iron-deficiency anemia and oral mucosal lesions in non-tobacco users, finding a significant association.

## Contribution

The study identifies specific oral lesions associated with iron-deficiency anemia in non-tobacco users.

## Key findings

- Iron-deficiency anemia is significantly associated with oral red and white mucosal lesions.
- Screening for these oral manifestations can help in early diagnosis and treatment of anemia.

## Abstract

The relation between hematological parameters and the presence of oral red and white mucosal lesions among non-tobacco-using adults
diagnosed with iron-deficiency anemia is of interest. Hematological parameters, including hemoglobin, serum ferritin, MCV, MCH and RDW,
were recorded. Clinical oral examinations identified red (erythroplakia, atrophic glossitis) and white lesions (oral candidiasis,
leukoplakia-like patches and angularcheilitis). There was a significant association between iron-deficiency anemia and specific oral
mucosal lesions among non-tobacco-using adults. Screening for oral manifestations can aid in early diagnosis and intervention in anemic
patients.

## Linked entities

- **Diseases:** iron-deficiency anemia (MONDO:0001356), oral candidiasis (MONDO:0005886), erythroplakia (MONDO:0023089), atrophic glossitis (MONDO:0001989), angular cheilitis (MONDO:0000741)

## Full-text entities

- **Genes:** ferritin [NCBI Gene 107789800]
- **Diseases:** iron-deficiency anemia (MESH:D018798), leukoplakia (MESH:D007971), mucosal lesions (MESH:D009059), oral candidiasis (MESH:D002180), atrophic glossitis (MESH:D005928)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## References

12 references — full list in the complete paper: https://tomesphere.com/paper/PMC12357697/full.md

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Source: https://tomesphere.com/paper/PMC12357697