# Clinical and biochemical profile among Indian patients with primary hyperparathyroidism

## TL;DR

The study examines the clinical and biochemical characteristics of 100 Indian patients with primary hyperparathyroidism from 2022 to 2024.

## Contribution

It highlights the high proportion of asymptomatic cases and evolving clinical patterns in primary hyperparathyroidism in India.

## Key findings

- 69% of patients were female with a mean age of 53.2 years.
- 49% of patients were asymptomatic with slightly higher mean age compared to symptomatic cases.
- Mean corrected serum calcium was 12.2 mg/dl and mean serum parathyroid hormone was 408.9 pg/ml.

## Abstract

Clinical and biochemical profile among Indian patients with primary hyperparathyroidism. Hence, a study was conducted from 2022 to
2024 at Mahatma Gandhi Medical College and Hospital, Jaipur, involving 100 patients diagnosed with primary hyperparathyroidism (PHPT).
The mean age was 53.2±14.5 years, with a female predominance (69%). Of all patients, 49% were asymptomatic and 51% were
symptomatic, with slightly higher mean age in asymptomatic individuals. Biochemically, the mean corrected serum calcium was
12.2±1.6 mg/dl and mean serum parathyroid hormone was 408.9±525.8 pg/ml. A high proportion of asymptomatic cases may
reflect improved nutritional status and routine serum calcium screening, highlighting the evolving clinical profile of PHPT.