# Nanoparticles revolution: The role of gold and chitosan in endodontics irrigation

**Authors:** Dipali Dinkar Deshpande, Varsha Pandit, Dhananjay Gunawat, Gauri Sanpurkar

PMC · DOI: 10.6026/973206300211239 · Bioinformation · 2025-05-31

## TL;DR

Gold and chitosan nanoparticles show promise in endodontic irrigation due to their antibacterial and anti-inflammatory properties.

## Contribution

The paper highlights the novel use of gold and chitosan nanoparticles in endodontic irrigation with unique antibacterial and biocompatible properties.

## Key findings

- Gold nanoparticles exhibit photo thermal and catalytic properties useful in disinfection.
- Chitosan nanoparticles provide natural antimicrobial and adhesive properties.
- Combined, these nanoparticles offer improved clinical treatment outcomes in endodontics.

## Abstract

The field of endodontic irrigation has seen nanoparticle innovations which offer improved disinfection together with better clinical
treatment results. Nanoparticles composed of gold and chitosan show significant antibacterial properties as well as anti-inflammatory
characteristics and biocompatibility potential. The photo thermal properties and catalytic properties are limited to gold nanoparticles
whereas the natural antimicrobial capabilities and adhesive properties are limited to chitosan nanoparticles. Nanoparticles play an
essential role in endodontic irrigation. However, more clinical work needs to be done to create standardized procedures using these new
agents.

## Linked entities

- **Chemicals:** gold (PubChem CID 23985), chitosan (PubChem CID 129662530)

## Full-text entities

- **Diseases:** inflammatory (MESH:D007249)
- **Chemicals:** chitosan (MESH:D048271), gold (MESH:D006046)

## Full text

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## References

33 references — full list in the complete paper: https://tomesphere.com/paper/PMC12357670/full.md

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Source: https://tomesphere.com/paper/PMC12357670