# Exploring anthropometric, biochemistry and nutritional attributes in overweight and obese women: Insights from the Serbian cohort: A pilot study

## TL;DR

This pilot study in Serbia found that specific anthropometric measures better predict cardiometabolic risks in overweight and obese women than BMI, with notable correlations to blood markers.

## Contribution

The study introduces a comprehensive analysis of multiple anthropometric indices and their associations with biochemical markers in a Serbian cohort of overweight and obese women.

## Key findings

- Triglycerides strongly correlate with VAI and CMI in overweight and obese women.
- HDL cholesterol shows strong negative correlations with VAI and CMI.
- Blood pressure correlates with WtHR and BMFI, but no significant differences in energy or macronutrient intake were found between groups.

## Abstract

Anthropometric measurements (AMs), such as waist circumference and body mass index (BMI), are dominant indicators of overweight and obesity. Nevertheless, other AMs, such as waist-hip ratio, waist circumference and indices of visceral adiposity index (VAI), body mass fat index (BMFI), cardiometabolic index (CMI) and waist-to-height ratio (WtHR) are more significant and discriminatory than BMI in predicting cardiometabolic risk.

This pilot study aimed to comprehensively investigate the anthropometric, biochemical and nutritional characteristics of a sample of overweight and obese women in Serbia, focusing on potential differences related to AM and its association with specific biochemical markers.

The final analytical sample consisted of 57 females (average age 37.16±7.27 years, range: 21-55 years). A strong positive correlation was observed between triglycerides (TG) and both the VAI (r=0.896, p<0.001) and the CMI (r=0.896, p<0.001), both with high statistical significance. Conversely, a strong negative correlation was found between high-density lipoprotein cholesterol (HDLc) and both VAI (r=-0.601, p<0.001) and CMI (r=-0.566, p<0.001). Systolic blood pressure (SBP) and diastolic blood pressure (DBP) were significantly positively correlated with both WtHR and BMFI: SBP and WtHR (r=0.343, p=0.009), SBP and BMFI (r=0.310, p=0.019), DBP and WtHR (r=0.368, p=0.005), and DBP and BMFI (r=0.377, p=0.004). The analysis of biochemical parameters indicated no significant differences between groups, except for TG levels, which were significantly higher in the obese group (p=0.045).

Although the AMs of the subjects were significantly different, energy intake and macronutrient intake were not significantly different. We did not find significant differences in the intake of most vitamins or minerals between the groups. Additionally, there is inadequate intake of essential nutrients such as vitamin D, iron and selenium, which are critical for overall health. Both groups did not meet the recommended folate intake, which may increase the risk of fetal neural tube defects.