# Clinicians’ attitudes and knowledge of medicinal cannabis in opioid dependence treatment clinics in New South Wales, Australia

**Authors:** Laila Parvaresh, Llewellyn Mills, Jaleh Gholami, Louisa Jansen, Nazila Jamshidi, Kate Baker, Christopher Tremonti, Marguerite Tracy, Adrian Dunlop, Nicholas Lintzeris

PMC · DOI: 10.1186/s42238-025-00315-6 · Journal of Cannabis Research · 2025-08-16

## TL;DR

This study explores the attitudes and knowledge of clinicians in opioid treatment clinics regarding medicinal cannabis use in Australia.

## Contribution

The study is the first to investigate OTP clinicians' perspectives on medicinal cannabis in opioid dependence treatment.

## Key findings

- Most clinicians lacked experience with medicinal cannabis and were unfamiliar with regulations.
- Over 70% of clinicians agreed to consider medicinal cannabis for health conditions in OTP clients.
- Educational needs focused on effectiveness evidence and indications for medicinal cannabis.

## Abstract

There are no prior studies investigating the attitudes and knowledge of opioid treatment program (OTP) clinicians on prescribed medicinal cannabis in OTP clients. This study examined the OTP clinicians' medicinal cannabis experience, knowledge, concerns, and educational needs.

Staff from six public OTP services in New South Wales completed a medicinal cannabis survey. Staff included nurses, doctors, pharmacists, allied health, and consumer workers. Single-level regression models were used to estimate participants’ sex, role, and year of experience effect.

102 (63%) clinicians responded to the medicinal cannabis part of the survey, mostly female (n = 58, 56.9%), and more than half worked full-time (n = 54, 52.9%). Most of the participants (88.5%, 85/96) lacked experience providing medicinal cannabis, two in three (66.7%, 68/102) agreed to consider medicinal cannabis as a treatment for addressing cannabis use in OTP clients. Over 70% (71.5%, 73/102) expressed similar agreement to consider medicinal cannabis for other health conditions in OTP clients. More than half of the clinicians (54.2%, 52/96) expressed a lack of confidence in assisting clients with accessing medicinal cannabis, and were unfamiliar with current regulations (56.2%, 54/96). Clinicians expressed safety concerns regarding side effects such as driving-related problems (74%, 71/96), cognitive impairment (54.2%, 52/96), and cannabis dependence (54.2%, 52/96). The three conditions most endorsed as having sufficient evidence to support the use of tetrahydrocannabinol (THC)-based medicinal cannabis were palliative care symptom management (72.4%, 71/98), chronic pain (67.4%, 66/98), and multiple sclerosis (43.8%, 43/98). The three conditions most identified as having sufficient evidence to support the routine clinical use of cannabidiol (CBD)-based medicinal cannabis were chronic pain (64.9%, 63/97), palliative care (62.5%, 60/96), and sleep problems (44.8%, 43/96). The most common educational needs identified by participants were the evidence for the effectiveness of medicinal cannabis in cannabis dependence treatment (88.5%, 85/96), other health conditions (87.5%, 84/96), and indications and contraindications for using medicinal cannabis (87.5%, 84/96).

Despite the interest in using medicinal cannabis for treating cannabis dependence and /or other health conditions, clinicians identified several barriers including limited experience, lack of confidence, and poor understanding of the regulatory framework.

The online version contains supplementary material available at 10.1186/s42238-025-00315-6.

## Full-text entities

- **Diseases:** borderline personality disorder (MESH:D001883), palliative care (MESH:D003428), PTSD (MESH:D013313), anxiety (MESH:D001007), psychosis (MESH:D011618), suicidal behaviour (MESH:D001523), Opioid dependence (MESH:D009293), LHDs (OMIM:603663), pain (MESH:D010146), Parkinson's disease (MESH:D010300), Sleep disorder (MESH:D012893), trauma (MESH:D014947), slowed thinking (MESH:D012897), depression (MESH:D003866), cognitive impairment (MESH:D003072), antisocial personality disorder (MESH:D000987), affective disorder (MESH:D019964), chronic pain (MESH:D059350), multiple sclerosis (MESH:D009103), respiratory and cardiovascular disease (MESH:D012140), opioid overdose (MESH:D000083682), addiction (MESH:D019966), cannabis (MESH:D002189), palliative care symptom (MESH:C000657744), opioid withdrawal (MESH:D013375)
- **Chemicals:** naloxone (MESH:D009270), methadone (MESH:D008691), THC-CBD (-), CBD (MESH:D002185), THC (MESH:D013759), Alcohol (MESH:D000438), buprenorphine (MESH:D002047)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

16 references — full list in the complete paper: https://tomesphere.com/paper/PMC12357479/full.md

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Source: https://tomesphere.com/paper/PMC12357479