# Madurella tropicana and Madurella pseudomycetomatis identified as new causative agents of black grain eumycetoma in Senegal

## TL;DR

This study identifies two new fungi causing a skin and soft tissue disease in Senegal and shows that molecular tools can accurately detect them.

## Contribution

The study identifies Madurella tropicana and Madurella pseudomycetomatis as new causative agents of eumycetoma in Senegal.

## Key findings

- Madurella tropicana and Madurella pseudomycetomatis were identified as new pathogens causing eumycetoma in Senegal.
- Molecular tools like ITS gene sequencing are essential for accurate species identification.
- Itraconazole treatment was effective in a patient infected with Madurella pseudomycetomatis.

## Abstract

This study reports Madurella tropicana and Madurella pseudomycetomatis as pathogens causing eumycetoma in Senegal. The dominant species, Madurella mycetomatis, shares morphological features with both. Accurate species-level identification is crucial for treatment and epidemiology. Molecular diagnostic tools, especially ITS gene sequencing, enabled the identification of these species. Itraconazole treatment showed a favorable outcome in a patient infected with Madurella pseudomycetomatis, leading to sinus closure.