# Rhabdomyosarcoma: A Case Report and Comprehensive Literature Review

**Authors:** Sebastián Dufner Krieger, Roberto A Hidalgo Ramos, Daniela Secades, Isaac Hong, Marcelo Ortiz

PMC · DOI: 10.7759/cureus.88028 · Cureus · 2025-07-15

## TL;DR

This paper presents a case of infantile rhabdomyosarcoma and reviews the importance of early diagnosis and treatment for better outcomes.

## Contribution

The novelty lies in the detailed case report of embryonal RMS in an infant and a synthesis of diagnostic and treatment insights.

## Key findings

- Early detection and multidisciplinary care improve prognosis in rhabdomyosarcoma.
- Orbital RMS in infants presents as a rapidly enlarging mass.
- Timely multimodal treatment is critical for managing RMS.

## Abstract

Rhabdomyosarcoma (RMS) is an uncommon and aggressive malignancy originating from mesenchymal tissue, frequently affecting children. Its clinical presentation can vary significantly depending on the tumor's location and histological subtype, often complicating timely diagnosis. Early recognition and the initiation of appropriate multimodal treatment are essential to improving outcomes. This report describes a case of embryonal RMS (ERMS) in a young infant with a rapidly enlarging orbital mass and provides an overview of relevant diagnostic considerations and treatment strategies. The case highlights the value of early detection and coordinated, multidisciplinary care in achieving the best possible prognosis.

## Linked entities

- **Diseases:** rhabdomyosarcoma (MONDO:0005212)

## Full-text entities

- **Diseases:** ERMS (MESH:D018233), RMS (MESH:D012208), malignancy (MESH:D009369), orbital mass (MESH:D009916)

## Full text

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## Figures

5 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12357001/full.md

## References

25 references — full list in the complete paper: https://tomesphere.com/paper/PMC12357001/full.md

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Source: https://tomesphere.com/paper/PMC12357001