# Neurosarcoidosis: A Case Report

**Authors:** Alejandro Cardona, Sofia Castro, Naomi Córdoba, Valeria Cardona

PMC · DOI: 10.7759/cureus.88041 · 2025-07-15

## TL;DR

This case report describes a rare neurological presentation of sarcoidosis, highlighting the importance of considering neurosarcoidosis in unexplained neurological events.

## Contribution

The novelty lies in presenting an atypical neurological onset of sarcoidosis without other clinical symptoms.

## Key findings

- Neurosarcoidosis can present with paroxysmal seizures and transient loss of consciousness.
- Neurological sarcoidosis should be considered in the differential diagnosis of unexplained neurological events.
- Infectious and neoplastic causes must be thoroughly excluded in such cases.

## Abstract

This case report presents an atypical manifestation of sarcoidosis with neurological onset, characterized by paroxysmal seizure episodes accompanied by transient loss of consciousness in the absence of other clinical symptoms. Although sarcoidosis usually presents with multisystem involvement, neurologic manifestations are rare. This case emphasizes the importance of including neurosarcoidosis in the differential diagnosis of unexplained neurological events, particularly when granulomatous disease is suspected, and underscores the need to thoroughly exclude infectious and neoplastic causes.

## Linked entities

- **Diseases:** sarcoidosis (MONDO:0008399), neurosarcoidosis (MONDO:0045047)

## Full-text entities

- **Diseases:** sarcoidosis (MESH:D012507), loss of consciousness (MESH:D014474), seizure (MESH:D012640), Neurosarcoidosis (MESH:C535814), granulomatous disease (MESH:D006105)

## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12354987/full.md

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Source: https://tomesphere.com/paper/PMC12354987