Road-Roller Technique Using Hyaluronidase-Enhanced Local Anaesthesia for Split-Thickness Skin Grafts
Pouya Mafi, Andrej Salibi

TL;DR
A new technique called the 'road-roller' uses hyaluronidase to spread local anesthesia more effectively for skin grafts, reducing discomfort and injection risks.
Contribution
The novel 'road-roller' technique combines hyaluronidase with lidocaine to achieve uniform anesthesia with a single injection for large skin grafts.
Findings
The road-roller technique provides effective and uniform anesthesia for large split-thickness skin graft donor sites.
Using hyaluronidase enhances local anesthetic diffusion, reducing the need for multiple injections and improving patient comfort.
The method is safe and reliable for skin cancer resection and reconstruction without exceeding safe anesthetic doses.
Abstract
Large split-thickness skin grafts (SSGs) can often be harvested under local anaesthesia, but traditional infiltration requires numerous needle passes across the donor area, which can cause significant discomfort and incomplete anaesthesia, not to mention the risk of exceeding weight-based lidocaine limits. We describe the "road-roller" technique: by combining lidocaine (with adrenaline) and hyaluronidase in one solution, injecting subdermally at the proximal edge of the graft donor area to raise a local bleb, and then using a tightly rolled gauze swab to firm-pressure-spread the anaesthetic "like a road roller", the entire donor site becomes uniformly anaesthetised with a single injection. This method improves patient comfort by avoiding multiple injections and provides a uniform block across the graft. We review the preparation of the anaesthetic mixture (including buffering),…
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Taxonomy
TopicsPharmaceutical studies and practices · Organ and Tissue Transplantation Research · Surgical Sutures and Adhesives
