# Utility of home doppler blood pressure measurement to minimise unnecessary investigations in children with suspected hypertension

**Authors:** Manson Chon In Kuok, Joanna Newton, Cheentan Singh, Manish D. Sinha

PMC · DOI: 10.1038/s41371-025-01038-0 · Journal of Human Hypertension · 2025-07-09

## TL;DR

Home Doppler blood pressure measurements can help avoid unnecessary tests in young children suspected of having hypertension.

## Contribution

The study demonstrates that home Doppler blood pressure monitoring can reduce unnecessary investigations in children under 5 with suspected hypertension.

## Key findings

- 90% of children referred for hypertension were normotensive after home Doppler blood pressure monitoring.
- Many initial investigations for secondary hypertension showed unremarkable results.
- Unnecessary second-line tests can be deferred until hypertension is confirmed.

## Abstract

An accurate measurement of blood pressure (BP) is essential in making a diagnosis of hypertension, however lack of reference values in children <5 years old makes out-of-office BP measurement using ambulatory blood pressure monitoring difficult in this age group. We conducted a retrospective analysis in children aged under 5 years referred to our hypertension service for suspected hypertension. We included those who underwent home doppler blood pressure measurement (HDBPM) for hypertension diagnosis confirmation, and evaluated the investigations performed for suspected hypertension before the diagnosis was confirmed using out-of-office  BP measurements. Children receiving anti-hypertensive medication at the time of initial review were excluded. Fifty-five children (62% male) with a median age of 1.6 years completed HDBPM and were included. Nearly 90% of them referred for hypertension were found to be normotensive following out-of-office BP assessment using HDBPM. In these normotensive patients, different investigations for secondary hypertension, including blood tests (creatinine, renin, aldosterone, cortisol, thyroid function tests, and catecholamine levels), doppler kidney ultrasound, and echocardiograms were performed before referral, most of which yielded unremarkable results. Our finding suggested that whilst some initial investigations were essential, second-line tests for less common secondary causes of hypertension are often unnecessary before hypertension is confirmed. We recommend deferring some of these investigations in asymptomatic children until hypertension is verified by home blood pressure measurements.

## Full-text entities

- **Genes:** REN (renin) [NCBI Gene 5972] {aka ADTKD4, HNFJ2, RTD}
- **Diseases:** hypertension (MESH:D006973)
- **Chemicals:** creatinine (MESH:D003404), aldosterone (MESH:D000450), catecholamine (MESH:D002395), cortisol (MESH:D006854)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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Source: https://tomesphere.com/paper/PMC12353806