# Rhino-Orbital Mucormycosis Presenting With Central Retinal Artery Occlusion: A Case Report

**Authors:** Irem Sena Sarac, Yasemin Aksu, Dilan Yildiz, Ahu Yilmaz

PMC · DOI: 10.7759/cureus.88020 · Cureus · 2025-07-15

## TL;DR

A diabetic woman with rhino-orbital mucormycosis developed severe complications including retinal artery occlusion and died despite treatment.

## Contribution

This case report highlights the rare presentation of central retinal artery occlusion in rhino-orbital mucormycosis.

## Key findings

- The patient had central retinal artery occlusion, cranial nerve palsies, and sinusitis caused by Rhizopus oryzae.
- Despite antifungal therapy and surgical debridement, the patient's condition was fatal.
- The case emphasizes the importance of early diagnosis and aggressive treatment in mucormycosis.

## Abstract

Rhino-orbital-cerebral mucormycosis (ROCM) is a severe fungal infection caused by opportunistic fungi of the order Mucorales, most commonly Rhizopus oryzae. It typically occurs in patients with diabetes mellitus or those who are immunocompromised. The diagnosis is based on histopathological, microbiological, clinical, and radiological findings. Early diagnosis is crucial, and management includes antifungal therapy and surgical debridement. In this case report, we report a 64-year-old diabetic female patient who presented with rhino-orbital mucormycosis. The patient had central retinal artery occlusion in the left eye, left cranial nerve palsies, and ethmoidal and maxillary sinusitis. The fungal culture examination resulted in Rhizopus oryzae. The patient received antifungal treatment and underwent left orbital exenteration and endoscopic sinus surgery. Despite antifungal treatment and early extensive surgical debridement, the patient died during the second month of intensive care.

## Linked entities

- **Diseases:** diabetes mellitus (MONDO:0005015), mucormycosis (MONDO:0019136)

## Full-text entities

- **Diseases:** ROCM (MESH:D009091), ethmoidal and maxillary sinusitis (MESH:D015521), Retinal Artery Occlusion (MESH:D015356), diabetes mellitus (MESH:D003920), cranial nerve palsies (MESH:D003389), fungal (MESH:D009181)
- **Species:** Homo sapiens (human, species) [taxon 9606], Rhizopus arrhizus (species) [taxon 64495]

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC12352933/full.md

## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12352933/full.md

## References

8 references — full list in the complete paper: https://tomesphere.com/paper/PMC12352933/full.md

---
Source: https://tomesphere.com/paper/PMC12352933