# Feasibility study for dose calculation with a radiation treatment planning system using a fixed-size electron cone applicator for small electron fields

**Authors:** Su Chul Han, Min Cheol Han, Jihun Kim, Heerim Nam, Jin Sung Kim, Kwangwoo Park

PMC · DOI: 10.1371/journal.pone.0324722 · PLOS One · 2025-08-14

## TL;DR

This study shows that a commercial radiation treatment planning system can accurately calculate doses for small electron fields using a fixed-size cone applicator with relative output factors.

## Contribution

A novel method for dose calculation using relative output factors for fixed-size electron cone applicators not natively supported by treatment planning systems.

## Key findings

- Gamma analysis showed >95% passing rate for depth dose comparisons and >99% for beam profiles.
- Monitor unit differences between TPS and measurements were within 2.0% for general applicators and 1.0% for fixed-size applicators.
- Dose distributions showed >99% agreement between TPS calculations and film measurements for fixed-size applicators.

## Abstract

This study aims to evaluate the feasibility of radiation treatment planning using a commercial treatment planning system (TPS) for small fixed-size electron cone electron applicators not natively supported by the TPS.

Dosimetric characteristics, including beam profiles and output factors (OFs), were compared between a 6 MeV electron beam collimated by a small fixed-size electron cone applicator and a cerrobend cutout-based general applicator. Measurements were performed using a micro-diamond detector in a water phantom for field sizes of 2, 3, 4, and 5 cm. The monitor units (MUs) from the TPS were compared with direct measurements. To estimate the MU for the fixed-size electron cone applicator using the TPS, the relative OFs were defined as the ratio of the OFs for the fixed-size electron cone and general applicators. Dose distributions obtained from the TPS were validated against measurements using Gafchromic films, ensuring accuracy.

Gamma analysis showed a passing rate >95% with 1%/1 mm criteria for depth dose comparisons and >99% with 2%/2 mm criteria for beam profiles. The general applicator’s OFs were consistently higher across all measured field sizes. The MU difference between the TPS and measurements was within 2.0%, while the difference between indirect TPS calculations and direct measurements for the fixed-size electron cone applicator remained within 1.0%. Dose distribution analysis showed >99% agreement (3%/3 mm) between the 2D dose distribution obtained using film in the fixed-size electron cone applicator and that calculated by the TPS of cerrobend cutout-based applicator.

The results demonstrate the feasibility of calculating monitor units and dose distributions for small fixed-size electron cone applicators using a commercial TPS combined with relative output factors. This approach offers a reliable method for dose calculation in specialized electron therapy applications.

## Full-text entities

- **Chemicals:** water (MESH:D014867)

## Full text

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## Figures

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## References

23 references — full list in the complete paper: https://tomesphere.com/paper/PMC12352773/full.md

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Source: https://tomesphere.com/paper/PMC12352773