# Infertility screening in unmarried women: A scoping review protocol

**Authors:** Sanam Borji-Navan, Nasser Mogharabian, Godwin Banafo Akrong, Godwin Banafo Akrong, Godwin Banafo Akrong, Godwin Banafo Akrong

PMC · DOI: 10.1371/journal.pone.0329899 · PLOS One · 2025-08-14

## TL;DR

This study outlines a plan to review what is known about infertility screening for unmarried women, aiming to improve understanding and care for this often-overlooked group.

## Contribution

The study introduces a systematic scoping review protocol focused on the under-researched topic of infertility screening in unmarried women.

## Key findings

- The review will map current screening practices and barriers for unmarried women.
- It will identify gaps in knowledge and guide future culturally sensitive interventions.
- Findings will be synthesized through narrative and visual summaries.

## Abstract

This scoping review aims to systematically map the landscape of infertility screening in unmarried women.

Infertility screening in unmarried women represents a significant and often neglected area within reproductive health. This population faces unique challenges and barriers, including social stigma, cultural norms, and limited access to care, making a comprehensive understanding of current screening practices essential.

Study selection will be guided by the PCCT framework (Population, Concept, Context, and study type), considering diverse study designs (quantitative, qualitative, mixed-methods, reviews) and grey literature, focusing on infertility screening in unmarried women.

This scoping review will follow the PRISMA-ScR guidelines and utilize a 14-step framework based on Arksey and O’Malley’s methodology, incorporating enhancements by Tricco and Peters. A comprehensive search strategy will be employed, using controlled vocabulary and free-text method. Databases of Web of Science (ISI), PubMed, Scopus and search engines like Google Scholar will be searched, and supplemented by forward and backward citation tracking. Inclusion/exclusion criteria will be applied iteratively. Two independent reviewers will screen titles/abstracts and full texts, resolving disagreements through consensus or a third reviewer. Data will be charted using a predefined template, and findings will be presented in tables and diagrams, accompanied by a narrative synthesis.

This scoping review will provide a comprehensive overview of the current state of knowledge regarding infertility screening in unmarried women, a significantly under-researched area. The findings will be critical for informing the development of culturally sensitive guidelines, targeted interventions, and future research to address the reproductive health needs of this underserved population.

## Full-text entities

- **Genes:** AMH (anti-Mullerian hormone) [NCBI Gene 268] {aka MIF, MIS}
- **Diseases:** ovulatory dysfunction (MESH:D006331), ACADEMIC EDITOR (MESH:D007859), tubal factor infertility (MESH:D005184), Infertility (MESH:D007246), male infertility (MESH:D007248), female infertility (MESH:D007247)
- **Chemicals:** PONE-D-25-15839R2 (-)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC12352679/full.md

## References

20 references — full list in the complete paper: https://tomesphere.com/paper/PMC12352679/full.md

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Source: https://tomesphere.com/paper/PMC12352679