# The interplay of prenatal stress and prenatal depression in Chinese couples: based on the actor-partner interdependence model

**Authors:** Xiaoqing Liu, Yuting Dong, Jungu Zhou, Shiying Lin, Minghuan Liu, Hang Zeng, Xiaowan Zhou, Yang Song, Xiaoxu Xie, Qiuping Liao, Shaowei Lin, Siying Wu

PMC · DOI: 10.3389/fpsyt.2025.1607470 · Frontiers in Psychiatry · 2025-07-31

## TL;DR

The study explores how prenatal stress and depression affect Chinese couples, finding that stress mainly impacts the individual rather than their partner.

## Contribution

The study applies the Actor-Partner Interdependence Model to examine spousal influences on prenatal depression in Chinese couples.

## Key findings

- Prenatal stress positively predicts an individual's own prenatal depression.
- Prenatal stress does not significantly influence the partner's depression.
- The actor-only pattern suggests minimal spousal influence on depression.

## Abstract

Pregnant women exhibit heightened stress susceptibility and elevated depression risk during gestation, factors associated with adverse outcomes including postpartum depression. Current research predominantly examines maternal experiences while neglecting spousal influences.

The study surveyed 282 Chinese married couples using validated scales to assess prenatal stress and depression. And analysed dyadic data from expectant parents using the Actor-Partner Interdependence Model (APIM) to determine the pattern of action of prenatal stress on prenatal depression between couples by calculating the magnitude of the ratio k between the partner effect and the actor effect.

The analysis revealed k1
 = 0.064, 95% CI: (-0.113, 0.260) and k2
 = 0.064, 95% CI: (-0.118, 0.249). The confidence intervals for both k1
 and k2
 included zero, indicating an actor-only pattern in the APIM. Specifically, prenatal stress positively predicted one’s own prenatal depression but did not significantly influence the partner’s depression.

It is crucial to encourage couples to actively manage their stress levels during the prenatal period. This can help to reduce the negative psychological effects of prenatal stress, which may lead to improved pregnancy outcomes and postnatal health.

## Linked entities

- **Diseases:** postpartum depression (MONDO:0005929)

## Full-text entities

- **Genes:** POLD4 (DNA polymerase delta 4, accessory subunit) [NCBI Gene 57804] {aka POLDS, p12}, H3P16 (H3 histone pseudogene 16) [NCBI Gene 644914] {aka H3.6, H3F3AP6, p21}, PSS (Potocki-Shaffer syndrome) [NCBI Gene 780904]
- **Diseases:** postpartum depression (MESH:D019052), diabetes (MESH:D003920), prenatal depression (MESH:D049188), psychiatric (MESH:D001523), hypertension (MESH:D006973), APIM (MESH:D004195), Depression (MESH:D003866), anxiety (MESH:D001007)
- **Chemicals:** cortisol (MESH:D006854)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12352324/full.md

## References

46 references — full list in the complete paper: https://tomesphere.com/paper/PMC12352324/full.md

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Source: https://tomesphere.com/paper/PMC12352324