# First person – Kishalay Ghosh and Rohit Iyer

PMC · DOI: 10.1242/bio.062123 · Biology Open · 2025-07-25

## TL;DR

This paper features an interview with Kishalay Ghosh and Rohit Iyer, who discuss their research on how cellular stress affects blood cell development in fruit flies.

## Contribution

The paper presents new insights into how genetic changes influence stress response and blood cell formation in Drosophila.

## Key findings

- Genetic perturbations affect cellular homeostasis and integrated stress response signaling.
- These changes regulate Drosophila hematopoiesis.
- The research highlights the role of stress response in blood cell development.

## Abstract

First Person is a series of interviews with the first authors of a selection of papers published in Biology Open, helping researchers promote themselves alongside their papers. Kishalay Ghosh and Rohit Iyer are co-first authors on ‘
Genetic perturbation of cellular homeostasis regulates integrated stress response signaling to control Drosophila hematopoiesis’, published in BiO. Kishalay conducted the research described in this article while a project associate in Dr Rohan J. Khadilkar's lab at the Advanced Centre for Treatment, Research and Education in Cancer (ACTREC), Tata Memorial Centre, Navi Mumbai, India. He is now a PhD student in the lab of Jaime De Juan-Sanz at ICM Paris Brain Institute, Hôpital Pitié, Paris, France, investigating metabolic regulation of neuronal circuit function and behaviour. Rohit is a project associate in the lab of Dr Rohan J. Khadilkar at ACTREC, India, investigating understanding the intricacies of host-pathogen interactions.

## Linked entities

- **Species:** Drosophila (taxon 7215)

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC12352274/full.md

## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12352274/full.md

## References

1 references — full list in the complete paper: https://tomesphere.com/paper/PMC12352274/full.md

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Source: https://tomesphere.com/paper/PMC12352274