# Draft genome of Staphylococcus epidermidis clinical isolate OGSA-Sep-145 from an implant-related spinal infection

**Authors:** Vincenzo Pennone, Matteo Briguglio, Elena De Vecchi, Riccardo Cecchinato, Arianna B. Lovati

PMC · DOI: 10.1128/mra.00416-25 · Microbiology Resource Announcements · 2025-06-24

## TL;DR

This paper presents the draft genome of a Staphylococcus epidermidis strain from a spinal infection, offering insights into its resistance and virulence.

## Contribution

The paper introduces a new draft genome from a clinical isolate linked to chronic implant-related infections.

## Key findings

- The genome provides insights into antimicrobial resistance mechanisms.
- It reveals potential virulence factors associated with chronic infections.

## Abstract

Staphylococcus epidermidis, a skin commensal, is a major cause of orthopedic implant-related infections due to its biofilm-forming ability and immune evasion strategies. Here, we present the draft genome of strain OGSA-Sep-145, isolated from a spinal infection, providing insights into antimicrobial resistance and virulence mechanisms in chronic infections.

## Linked entities

- **Species:** Staphylococcus epidermidis (taxon 1282)

## Full-text entities

- **Diseases:** infections (MESH:D007239)
- **Species:** Staphylococcus epidermidis (species) [taxon 1282]
- **Cell lines:** OGSA-Sep-145 — Homo sapiens (Human), Induced pluripotent stem cell (CVCL_JU27)

## Full text

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## Figures

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## References

12 references — full list in the complete paper: https://tomesphere.com/paper/PMC12352096/full.md

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Source: https://tomesphere.com/paper/PMC12352096