# Seven genome sequences of Rothia spp. isolated from human saliva

**Authors:** Allen Choi, Lindsey Pia, Justin R. Kaspar

PMC · DOI: 10.1128/mra.00465-25 · Microbiology Resource Announcements · 2025-07-07

## TL;DR

This paper presents the complete genome sequences of seven Rothia bacteria strains from human saliva, highlighting two species with different genetic compositions.

## Contribution

The study provides new genome sequences for understudied Rothia species, expanding knowledge of their genetic diversity.

## Key findings

- Seven Rothia strains were sequenced, including four R. mucilaginosa and three R. dentocariosa.
- Genome GC content differed between species, with R. mucilaginosa at 59.5% and R. dentocariosa at 53.8%.

## Abstract

Rothia are understudied commensal bacteria within the human oral cavity and respiratory tract and can cause opportunistic infections. We report the complete genome sequences of seven Rothia spp. strains isolated from pooled human saliva, including four strains of Rothia mucilaginosa (59.5% GC) and three strains of Rothia dentocariosa (53.8% GC).

## Linked entities

- **Species:** Rothia mucilaginosa (taxon 43675), Rothia dentocariosa (taxon 2047)

## Full-text entities

- **Diseases:** opportunistic infections (MESH:D009894)
- **Species:** Rothia dentocariosa (species) [taxon 2047], Rothia (genus) [taxon 508215], Homo sapiens (human, species) [taxon 9606], Rothia mucilaginosa (species) [taxon 43675]

## Full text

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## References

16 references — full list in the complete paper: https://tomesphere.com/paper/PMC12352080/full.md

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Source: https://tomesphere.com/paper/PMC12352080