# Associations of perceived stress with depression in medical students: the mediating role of rumination and the moderating role of emotional intelligence

**Authors:** Youjuan Hong, Lina Luo, Zixuan Li, Siyu Wu, Xiaofan Bao

PMC · DOI: 10.3389/fpsyg.2025.1620067 · 2025-07-31

## TL;DR

This study shows that stress increases depression in medical students, partly through rumination, and emotional intelligence can reduce this effect.

## Contribution

The study identifies rumination as a mediator and emotional intelligence as a moderator in the stress-depression link among medical students.

## Key findings

- Perceived stress and rumination are strongly positively linked to depression in medical students.
- Rumination mediates 31.67% of the stress-depression relationship.
- Emotional intelligence moderates the direct effect of stress on depression.

## Abstract

Medical students have become a group with a high prevalence of depression and are particularly vulnerable to it. Recognizing the factors affecting depression among medical students is crucial. This study was aimed at exploring the effects of perceived stress on medical students’ depression under the mediating role of the rumination and the moderating role of the emotional intelligence.

A survey was conducted with 648 medical students in XX Province, XX (blind review). Participants provided responses to measures of perceived stress, rumination, emotional intelligence, and depression. Data analysis was performed in SPSS version 26 and the SPSS PROCESS Macro.

The results revealed significant positive associations between perceived stress (r = 0.63, p < 0.01) and rumination (r = 0.59, p < 0.01) with depression. Rumination plays a mediating role between perceived stress and depression, with the mediation effect accounting for 31.67% (SE = 0.10, 95% CI = 0.15, 0.26). Furthermore, emotional intelligence significantly moderated the direct effect (moderated mediation = −0.01, SE = 0.01, 95% CI = −0.01, −0.00).

Rumination serves as a mediator in the relationship between perceived stress and depression, while emotional intelligence significantly moderates the impact of perceived stress on depression.

## Linked entities

- **Diseases:** depression (MONDO:0002050)

## Full-text entities

- **Diseases:** depression (MESH:D003866)

## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12350455/full.md

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Source: https://tomesphere.com/paper/PMC12350455