# Unveiling Facklamia: detection of an emerging microbe in the skin microbiome of patients with filarial lymphedema

**Authors:** Danapriyaa Dharmalingam, Janani Semalaiyappan, Sankari Thirumal, Vijesh Sreedhar Kuttiatt

PMC · DOI: 10.3389/fcimb.2025.1624288 · 2025-07-31

## TL;DR

Facklamia, a rare microbe, was found in the skin of patients with filarial lymphedema, suggesting a possible link to their condition.

## Contribution

This is the first report of Facklamia detection in filarial lymphedema patients.

## Key findings

- Facklamia was detected in the skin microbiome of three filarial lymphedema patients.
- This is the first known association of Facklamia with filarial lymphedema.
- Further research is needed to understand Facklamia's role in skin infections.

## Abstract

Facklamia is an emerging pathogen in human beings and only a few clinical cases were reported in the literature. We detected the presence of this unusual microbe among the skin flora of three patients with filarial lymphedema in a 16S rRNA-based metagenomic study on the skin microbiome. To our knowledge, this is the first report of detection of this microbe in patients affected with filarial lymphedema. Further investigations are required to elucidate the role of Facklamia in secondary skin and soft tissue infection of filarial lymphedema patients.

## Linked entities

- **Species:** Facklamia (taxon 66831)

## Full-text entities

- **Diseases:** skin and soft tissue (MESH:D017695), infection (MESH:D007239), filarial lymphedema (MESH:D062846)
- **Species:** Facklamia (genus) [taxon 66831], Homo sapiens (human, species) [taxon 9606]

## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC12350424/full.md

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Source: https://tomesphere.com/paper/PMC12350424