# Kidney transplantation between identical twins with APOL1 homozygote risk alleles – a case report

## TL;DR

A case report describes successful kidney transplantation between identical twins with a high-risk APOL1 gene variant.

## Contribution

Demonstrates successful transplantation outcomes despite high-risk APOL1 genotype in identical twins.

## Key findings

- Identical twins with APOL1 homozygote risk alleles underwent successful living kidney transplantation.
- Short-term outcomes for both donor and recipient were excellent.

## Abstract

Kidney transplantation is the optimal therapy for individuals with end-stage kidney disease. Recent studies suggest a negative impact of high-risk Apolipoprotein L1 genotypes on outcomes for both living kidney donors and kidney transplant recipients. In this case, we describe a pair of identical twins with a high-risk APOL1 genotype who underwent successful living kidney transplantation with excellent short-term outcomes.