Authors’ Reply: Clarifying Blood Indices in Patients With Ovarian Cancer
Jiahua Zhang

Abstract
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TopicsNutrition and Health in Aging · Childhood Cancer Survivors' Quality of Life · Cancer survivorship and care
We agreed with the authors of the letter to the editor [1] that Figure 7 simply describes “the changes in blood cells.” Our study [2] only focused on the effect of nutritional status on the inflammatory response of the patients but neglected an important point: the changes in blood cells such as “leukocytes, lymphocytes, neutrophils, and platelets” were also closely related to the occurrence of bone marrow suppression (BMS) in the patients [3]. Figure 7 illustrates that the nutritional intervention program in this study can reduce the occurrence of BMS in patients to a certain extent.
We couldn’t agree more with the letter’s suggestion. We would like to include the benefits of improved BMS in the Discussion section of our study, which would primarily include the following:
The reference list from the paper itself. Each links out to its DOI / PubMed record.
- 1Lian C Fan Y Li J Clarifying blood indices in patients with ovarian cancer JMIR Mhealth Uhealth 202513 e 70895 doi 10.2196/7089540802962 PMC 12349733 · doi ↗ · pubmed ↗
- 2Tian X Liu Y Zhang J et al Efficacy of a We Chat-Based, multidisciplinary, full-course nutritional management program on the nutritional status of patients with ovarian cancer undergoing chemotherapy: randomized controlled trial JMIR Mhealth Uhealth Nov 4202412 e 56475 doi 10.2196/56475 Medline 39496160 PMC 11554286 · doi ↗ · pubmed ↗
- 3Ten Berg MJ van den Bemt PMLA Shantakumar S et al Thrombocytopenia in adult cancer patients receiving cytotoxic chemotherapy: results from a retrospective hospital-based cohort study Drug Saf Dec 12011341211511160 doi 10.2165/11594310-000000000-00000 Medline 22077503 · doi ↗ · pubmed ↗
- 4Crawford J Herndon D Gmitter K Weiss J The impact of myelosuppression on quality of life of patients treated with chemotherapy Future Oncol 2024202115151530 doi 10.2217/fon-2023-0513 Medline 38587388 PMC 11441072 · doi ↗ · pubmed ↗
- 5Crawford J Moore DC Morrison VA Dale D Use of prophylactic pegfilgrastim for chemotherapy-induced neutropenia in the US: a review of adherence to present guidelines for usage Cancer Treat Res Commun 202129100466 doi 10.1016/j.ctarc.2021.100466 Medline 34655862 · doi ↗ · pubmed ↗
- 6Bryer E Henry D Chemotherapy-induced anemia: etiology, pathophysiology, and implications for contemporary practice Int J Clin Transfus Oct 23201862131 doi 10.2147/IJCTM.S 187569 · doi ↗
- 7Thrombocytopenia (low platelet count)American Cancer Society UR Lhttps://www.cancer.org/cancer/managing-cancer/side-effects/low-blood-counts/bleeding.html Accessed 06-08-2025
