# Evaluation of the Modified Early Warning Score (MEWS) in In-Hospital Cardiac Arrest in a Tertiary Healthcare Facility

**Authors:** Osakpolor Ogbebor, Sitara Niranjan, Vikram Saini, Deeksha Ramanujam, Briana DiSilvio, Tariq Cheema

PMC · DOI: 10.3390/jcm14155384 · 2025-07-30

## TL;DR

This study evaluates how the Modified Early Warning Score (MEWS) changes before in-hospital cardiac arrests, suggesting it could help identify at-risk patients up to 6 hours in advance.

## Contribution

The study provides new evidence that MEWS trends can predict cardiac arrest up to 6 hours before the event.

## Key findings

- MEWS increased significantly from 12 hours to 1 hour before cardiac arrest (p ≤ 0.001).
- Only 20.7% of patients who had a cardiac arrest survived to hospital discharge.
- MEWS increased from 6 hours to 1 hour before cardiac arrest (p = 0.023).

## Abstract

Background/Objective: In-hospital cardiac arrest has high incidence and poor survival rates, posing a significant healthcare challenge. It is important to intervene in the hours before the cardiac arrest to prevent poor outcomes. The modified early warning score (MEWS) is a validated tool for identifying a deteriorating patient. It is an aggregate of vital signs and level of consciousness. We retrospectively evaluated MEWS for trends that might predict patient outcomes. Methods: We performed a single-center, one-year, retrospective study. A comprehensive review was conducted for patients aged 18 years and above who experienced a cardiac arrest. Cases that occurred within an intensive care unit, emergency department, during a procedure, or outside the hospital were excluded. A total of 87 cases met our predefined inclusion criteria. We collected data at 12 h, 6 h and 1 h time periods prior to the cardiac arrest. A trend analysis using a linear model with analysis of variance with Bonferroni correction was performed. Results: Out of 87 patients included in the study, 59 (67.8%) had an immediate return of spontaneous circulation (ROSC). Among those who achieved ROSC, 41 (69.5%) died during the admission. Only 20.7% of the patients that sustained a cardiac arrest survived to discharge. A significant increase in the average MEWS was noted from the 12 h period (MEWS = 3.95 ± 2.4) to the 1 h period (MEWS = 5.98 ± 3.5) (p ≤ 0.001) and the 6 h period (4.65 ± 2.6) to the 1 h period (5.98 ± 3.5) (p = 0.023) prior to cardiac arrest. Conclusions: An increase in the MEWS may be a valuable tool in identifying at-risk patients and provides an opportunity to intervene at least 6 h before a cardiac arrest event. Further research is needed to validate the results of our study.

## Full-text entities

- **Diseases:** died (MESH:D003643), Cardiac Arrest (MESH:D006323)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12347974/full.md

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Source: https://tomesphere.com/paper/PMC12347974