# Transforaminal Lumbar Interbody Fusion (TLIF) with Expandable Banana-Shaped Interbody Spacers—Institutional 5-Year Experience

**Authors:** Martin N. Stienen, Lorenzo Bertulli, Gregor Fischer, Linda Bättig, Yesim Yildiz, Laurin Feuerstein, Francis Kissling, Thomas Schöfl, Felix C. Stengel, Daniele Gianoli, Stefan Motov, Ethan Schonfeld, Anand Veeravagu, Benjamin Martens, Nader Hejrati

PMC · DOI: 10.3390/jcm14155402 · 2025-07-31

## TL;DR

This study examines the safety and effectiveness of using expandable titanium spacers in TLIF surgeries over five years, showing good clinical outcomes and successful spine alignment.

## Contribution

The study provides a large single-center experience with expandable TLIF spacers, highlighting their safety and effectiveness in restoring spinal alignment.

## Key findings

- 74.1% of patients had good or excellent clinical outcomes at 3 months, and 71.8% at 12 months.
- Radiographic fusion was achieved in 73.1% of segments at 12 months with significant improvement in segmental lordosis.
- No device failures or device-associated complications were observed during the follow-up period.

## Abstract

Background: Transforaminal lumbar interbody fusion (TLIF) with static cages is a frequently performed procedure. Larger series focusing on the use of expandable TLIF spacers are less common. Methods: This retrospective, single-center observational cohort study reviewed consecutive patients treated by TLIF using expandable titanium interbody implants (ALTERA™, Globus Medical Inc., Audubon, PA, USA) for degenerative pathologies from L2-S1 between 11/2018 and 09/2023. Surgical parameters, adverse events, radiological outcomes (fusion rate, segmental lordosis, spinopelvic parameters), and clinical outcomes were analyzed through a mean postoperative follow-up of 12 months. Results: This study identified 270 patients (mean age 65 years, 50.4% female) who underwent TLIF with expandable interbody spacers at 324 levels. Clinical outcomes were good or excellent in 74.1% of patients at 3 months and 71.8% at 12 months. Radiographic fusion was achieved in 73.1% of assessable segments at 12 months. Segmental lordosis increased significantly from 17.8° preoperatively to 20.0° at 12 months (p < 0.001). Adverse event (AE) rates were acceptable across all timepoints, with no device failures or device-associated complications observed. Conclusions: This study demonstrates that TLIF with expandable titanium interbody implants was safe, associated with high fusion rates, and enabled significant restoration of segmental lordosis that was maintained during follow-up.

## Full-text entities

- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12347699/full.md

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Source: https://tomesphere.com/paper/PMC12347699