# Button Cystostomy in Children with Neurogenic Bladder: Outcomes from a Single Center

**Authors:** Michela Galati, Rebecca Pulvirenti, Ida Barretta, Noemi Deanesi, Chiara Pellegrino, Antonio Maria Zaccara, Maria Luisa Capitanucci, Giovanni Mosiello

PMC · DOI: 10.3390/jcm14155532 · Journal of Clinical Medicine · 2025-08-06

## TL;DR

Button cystostomy is a safe and effective alternative for children with neurogenic bladder who cannot perform clean intermittent catheterization.

## Contribution

This study provides long-term outcomes of button cystostomy in pediatric neurogenic bladder patients, highlighting its safety and effectiveness.

## Key findings

- Button cystostomy had a low complication rate and high family satisfaction in children with neurogenic bladder.
- Most patients had spinal dysraphism, and the procedure had a short mean operative time of 48.5 minutes.
- Five patients experienced febrile UTIs, but no major complications occurred during follow-up.

## Abstract

Background: Neurogenic bladder (NB) in children may lead to recurrent urinary tract infections (UTIs), renal deterioration, and a reduced quality of life. Clean intermittent catheterization (CIC) is the standard of care, but in some patients, CIC may be unfeasible due to anatomical, sensory, or compliance issues. Button cystostomy (BC) has emerged as a minimally invasive, bladder-preserving alternative. This study aimed to assess the feasibility, safety, and outcomes in the long-term of BC in pediatric NB patients. Methods: Retrospective analysis was conducted on children with NB who underwent endoscopic BC placement between January 2020 and December 2024 in a tertiary pediatric center. Demographic data, operative time, complications, and follow-up outcomes were collected. All procedures used an endoscopic approach with cystoscopic guidance for safe device placement. Results: Thirty-three patients (25 males; median age 7.96 years) underwent BC placement. Most had spinal dysraphism (63.6%). The mean operative time was 48.5 ± 6 min. During a mean follow-up of 2.1 ± 1.4 years, five patients (15.2%) had febrile UTIs and two had minor leakage. No major complications occurred. Four buttons were removed due to clinical improvement (N = 1), the fashioning of a continent derivation (N = 1) and implantation of a sacral neuromodulator (N = 2); two patients accepted CIC. Satisfaction was reported by 93.9% of families. Conclusions: BC is an effective, minimally invasive alternative for urinary drainage in children with NB, even when compared to continent diversion techniques such as the Mitrofanoff, due to its lower invasiveness, greater feasibility, and lower complication rate. Broader adoption may be warranted, but prospective studies are needed to confirm long-term outcomes.

## Linked entities

- **Diseases:** neurogenic bladder (MONDO:0001445)

## Full-text entities

- **Diseases:** complication (MESH:D008107), UTIs (MESH:D014552), spinal dysraphism (MESH:D016135), NB (MESH:D001750), renal deterioration (MESH:D058186)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## References

25 references — full list in the complete paper: https://tomesphere.com/paper/PMC12347148/full.md

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Source: https://tomesphere.com/paper/PMC12347148