# Research Progress on the Effect of Thesium chinense Turcz. on Neurodegenerative Diseases

## TL;DR

This review explores how Thesium chinense Turcz., a Chinese herb, may help treat neurodegenerative diseases through its anti-inflammatory and neuroprotective properties.

## Contribution

The paper systematically reviews the mechanisms and preclinical evidence of Thesium chinense Turcz.'s effects on neurodegenerative diseases.

## Key findings

- Active components of Thesium chinense Turcz. modulate neuroinflammation and oxidative stress in neurodegenerative diseases.
- Preclinical studies show neuroprotective efficacy of the herb in experimental models.
- The herb has translational potential for developing natural product-based therapies for neurodegenerative diseases.

## Abstract

Thesium chinense Turcz., a traditional Chinese medicinal herb, is enriched with bioactive constituents such as flavonoids and polysaccharides, demonstrating multifaceted therapeutic properties including anti-inflammatory, antioxidant, and neuroprotective effects. This review systematically elucidates the regulatory mechanisms by which active components of Thesium chinense Turcz. modulate pathological processes in NDDs, such as neuroinflammation and oxidative stress. Furthermore, it synthesizes evidence of its neuroprotective efficacy across experimental models and evaluates its translational potential for clinical applications. By integrating preclinical findings and mechanistic insights, this work provides a robust theoretical foundation for advancing natural product-based therapeutics in the management of NDDs.